Poor response to treatment of renal anaemia with erythropoietin corrected by iron given intravenously.

نویسندگان

  • I C Macdougall
  • R D Hutton
  • I Cavill
  • G A Coles
  • J D Williams
چکیده

human immunodeficiency virus infection in haemophiliacs. Lancet 1986;ii: 1233-6. 12 Centers for Disease Control. Classification system for human T-lymphotropic virus type Illymphadenopathy-associated virus infections. Ann Intern Med 1986;105:234-7. 13 Centers for Disease Control. Revision of the case definition of acquired immunodeficiency syndrome for national reporting. MMWR 1985;34: 374-5. 14 Peto K, Pike MC, Armitage DR, et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples. BrJ Cancer 1977;35:1-39. 15 Haseltine WA. Replication and pathogenesis of the AIDS virus. Journal of AIDS 1988;1:217-40. 16 Pedersen C, Nielsen JO, Dickmeiss E, Jordal R. Early progression to the acquired immunodeficiency syndrome following primary human immunodeficiency virus infection. AIDS (in press). 17 Scott GB, Buck BE, Leterman JG, Bloom FL, Parks WP. Acquired immunodeficiency syndrome in infants. N EnglJ Med 1984:310:76-8 1. 18 Anderson KC, Gorgone BC, Marlink RG, et al. Transfusion-acquired human immunodeficiency virus infection among immunocompromised persons. Ann Intern Med 1986;105:519-27. 19 Cooper DA, Gold J, Maclean P, etal. Acute AIDS retrovirus infection. Lancet 1985;i:537-40. 20 Ho DD, Sarngadharan MG, Resnick L, Dimaszo-Veronese R, Rota TR, Hirsch MS. Primary human T-lymphotropic virus type III infection. Ann Intern Med 1985;103:880-3. 21 Tindall B, Barker S, Donovan B, et al. Characterization of the acute clinical illness associated with human immunodeficiency virus infection. Arch Intern Med 1988;148:945-9. 22 Weber JN, Rogers LA, Scott K, et al. Three-year prospective study ofHTLV III infection in homosexual men. Lancet 1986;i: 1179-82. 23 Boyko WJ, Schenchter MT, Craib KJP, et al. The Vancouver lymphadenopathy-AIDS study: 7. Clinical and laboratory features of 87 cases of primary HIV infection. CMAJ 1987;137:109-13. 24 Lange JMA, Parry JV, de Wolf F, Mortimer PP, Goudsmit J. Diagnostic value of specific IgM antibodies in primary HIV infection. AIDS 1988;2:31-5. 25 Pedersen C, Gerstoft J, Lindhardt B0, Sindrup J. Candida esophagitis associated with acute human immunodeficiency virus infection. J Infect Dis 1987;156:529-30. 26 Rouse BT, Horohov DW. Immunosuppression in viral infections. Rev Infect Dis 1986;8:850-73.

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منابع مشابه

The use of erythropoietin in renal failure.

The treatment of renal anaemia by recombinant human erythropoietin (EPO) is now well established. Several studies have examined the pharmacokinetics and efficacy of the drug given intravenously, intraperitoneally and subcutaneously and there is increasing evidence that the subcutaneous route has several advantages including the requirement for a lower dose. It is also important to stress the ne...

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The treatment of renal anaemia by recombinant human erythropoietin (EPO) is now well established. Several studies have examined the pharmacokinetics and efficacy of the drug given intravenously, intraperitoneally and subcutaneously and there is increasing evidence that the subcutaneous route has several advantages including the requirement for a lower dose. It is also important to stress the ne...

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PHARMA COKINETICS OF RECOMBINANT ERYTHROPOIETIN AND RED CELL METABOLISM IN HAEMODIALYSIS PATIENTS

The pharmacokinetics of recombinant human erythropoietin (rHuEpo) administered intravenously has been investigated in a group of five patients with chronic renal failure who were dialysis-dependent. The half-life of circulating erythropoietin decreased from 7.9±OA hr (mean ±SO) at the beginning of treatment to 6.2±O.6 hr after 6 weeks and 5A±O.9 hr after 4 months of treatment. In spite of t...

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Cancer-related anaemia requires higher doses of epoetin alfa than chronic renal failure replacement therapy.

Epoetin alfa has been used effectively for over a decade as hormone replacement therapy in the treatment of anaemia in patients with chronic renal failure (chronic kidney disease). In this condition, erythropoietin production is impaired and the resulting deficiency is the primary cause of the normocytic, normochromic anaemia typically observed w1x. The recommended initial epoetin alfa dosages ...

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Management of iron deficiency anaemia in gynaecological patients at Jinnah Postgraduate Medical Centre, Karachi.

OBJECTIVE To determine the efficacy and safety of subcutaneously administered recombinant human erythropoietin in combination with intravenous iron sucrose for the management of iron deficiency anaemia in gynaecological patients in Jinnah Postgraduate Medical Centre Karachi. METHODS It was an interventional quasi experimental study carried out in the Department of Obstetrics /Gynaecology, at ...

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Renal association clinical practice guideline on Anaemia of Chronic Kidney Disease

Anaemia is a commonly diagnosed complication among patients suffering with chronic kidney disease. If left untreated, it may affect patient quality of life. There are several causes for anaemia in this patient population. As the kidney function deteriorates, together with medications and dietary restrictions, patients may develop iron deficiency, resulting in reduction of iron supply to the bon...

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عنوان ژورنال:
  • BMJ

دوره 299 6692  شماره 

صفحات  -

تاریخ انتشار 1989